STAIN NAME

Actin

ANTIBODY

(HHF35) Muscle Specific

DESCRIPTION

Helps to identify smooth muscle tumor and myoepithelial cells

STAIN NAME

AE1/AE3 (Cytokeratin Cocktail)

ANTIBODY

Cytokeratin AE1/AE3

DESCRIPTION

Can be used to differentiate epithelial from non-epithelial tumors

STAIN NAME

AFP (Alpha-1-Fetoprotein)

ANTIBODY

Polyclonal Anti-human

DESCRIPTION

Helps to identify hepatocellular carcinomas, gonadal and extragonadal yolk sac tumors and mixed germ cell tumors

STAIN NAME

ALK-1

ANTIBODY

ALK-1

DESCRIPTION

Helps to identify anaplastic large cell lymphomas

STAIN NAME

AMACR (P504S)

ANTIBODY

13H4

DESCRIPTION

Aids in the classification of premalignant high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma

STAIN NAME

Androgen Receptor

ANTIBODY

Monoclonal Mouse Androgen Receptor

DESCRIPTION

In skin, positive staining has been observed in cells of hair follicles, sweat glands and squamous cells of the epidermis. In adenocarcinomas of the prostate androgen receptor has been demonstrated by IHC to be present in the nuclei of most neoplastic cell with neuroendocrine differentiation. Strong to moderate expressions in cervical, ovarian cells and placenta.

STAIN NAME

APP (Amyloid Precursor Protein)

ANTIBODY

APP

DESCRIPTION

Helps with the identification of Alzheimer’s Disease

STAIN NAME

Arginase-1

ANTIBODY

Rabbit Monoclonal

DESCRIPTION

Helps to distinguish hepatocellular carcinoma from a metastatic tumor to the liver

STAIN NAME

BCL1 (Cyclin D1)

ANTIBODY

SP4

DESCRIPTION

Useful in identification of mantle cell lymphomas

STAIN NAME

BCL2

ANTIBODY

Clone 124

DESCRIPTION

Useful in identification of follicular lymphomas and disease progression

STAIN NAME

BCL6

ANTIBODY

PG-B6p

DESCRIPTION

Useful in identification of follicular lymphoma, DLBCL and Burkitt Lymphoma

STAIN NAME

BER-EP4 (Epithelial Antigen)

ANTIBODY

BER-EP4

DESCRIPTION

Helps to differentiate carcinomas from mesotheliomas

STAIN NAME

Beta-Catenin

ANTIBODY

Beta-Catenin

DESCRIPTION

Used to distinguish deep fibromatosis from other benign and malignant fibroblastic and
myofibroblastic lesion, primary adenocarcinoma of the bladder and secondary involvement by
colorectal adenocarcinoma, distinguish hepatocellular carcinoma from focal nodular
hyperplasia, and aid in the diagnosis of solid pseudopapillary neoplasms

STAIN NAME

CA125

ANTIBODY

M11

DESCRIPTION

Useful in the idenification of ovarian carcinomas

STAIN NAME

CA19-9

ANTIBODY

116-NS-19-9

DESCRIPTION

Useful in the identification of GI carcinoma

STAIN NAME

Calponin

ANTIBODY

Clone CALP

DESCRIPTION

Myoepithelial marker, in situ vs. infiltrating breast carcinoma

STAIN NAME

Calretinin

ANTIBODY

DAK Calret 1

DESCRIPTION

Most specific and reproducible positive marker of epithelial mesothelioma

STAIN NAME

CAM 5.2

ANTIBODY

CAM 5.2

DESCRIPTION

This antibody is used to aid in the identification of tumors of epithelial origin and in
distinguishing carcinomas from other malignant tumors of non-epithelial origin

STAIN NAME

Carbonic Anhydrase (CA IX)

ANTIBODY

M75

DESCRIPTION

Helpful in clear cell renal cell carcinoma, and strong diffuse-to multifocal staining in large
majority of urothelial carcinomas, as opposed to extremely weak and focal staining in collecting
duct carcinoma

STAIN NAME

CD10

ANTIBODY

56C6

DESCRIPTION

Expressed in early lymphoid progenitor and normal germinal center cells

STAIN NAME

CD117

ANTIBODY

c-kit (polyclonal)

DESCRIPTION

Aid in the differentiation of GIST, management of (Gleevec®) therapy

STAIN NAME

CD138

ANTIBODY

MI 15

DESCRIPTION

Positive in B-cell precursors, plasma cells, myeloma

STAIN NAME

CD15

ANTIBODY

Carb-3

DESCRIPTION

Useful in the identification of Reed-Sternberg cells and Hodgkin lyphomas

STAIN NAME

CD163

ANTIBODY

MRQ-26

DESCRIPTION

Anti-CD163 labels cells of monocytic-macrophage lineage, with expression in bone marrow and histiocytic neoplasms.

STAIN NAME

CD1a

ANTIBODY

Clone: 010

DESCRIPTION

Expressed on cortical thymocytes, Langerhans cells, and dendritic cells

STAIN NAME

CD2

ANTIBODY

AB75

DESCRIPTION

Labels CD2-expressing normal T cells and related neoplasms. Results aid in the classification of precursor T-cell lymphoma, peripheral
T-cell lymphoma, and anaplastic large cell lymphoma.

STAIN NAME

CD20

ANTIBODY

Pan B-Cell

DESCRIPTION

Labels normal and neoplastic B-cells and if absent from plasma cells

STAIN NAME

CD21

ANTIBODY

IF8

DESCRIPTION

Expressed on mature B-cells, folllicular dendritic cells (FDC)

STAIN NAME

CD23

ANTIBODY

DAK-CD23

DESCRIPTION

Useful in distinguishing B-cells CLL/SLL from other entities

STAIN NAME

CD25

ANTIBODY

4C9

DESCRIPTION

CD25 has been detected in various hematological malignancies including adult T-cell leukemia/lymphoma, and hairy cell leukemia

STAIN NAME

CD3

ANTIBODY

Pan T-cell

DESCRIPTION

Labels normal and neoplastic T-cells

STAIN NAME

CD3/CD20

ANTIBODY

CD3/CD20 double stain

DESCRIPTION

Differentiates between B and T cells

STAIN NAME

CD30

ANTIBODY

BER-H2

DESCRIPTION

Labels Reed-Sternberg cells, ALCL, T-cell lymphomas, germ cell tumors

STAIN NAME

CD31

ANTIBODY

JC7041

DESCRIPTION

Endothelial cells and prognostic marker for tumor angiogenesis

STAIN NAME

CD34

ANTIBODY

Hematopoietic Progenitor QBEnd 10

DESCRIPTION

Expressed on lymphoid, myeloid, endothelial GIST

STAIN NAME

CD4/CD8

ANTIBODY

MT310 & DK25

DESCRIPTION

Used to differentiate cutaneous T-cell lymphomas, including mycoses fungoides

STAIN NAME

CD43

ANTIBODY

T-cell DF-T1

DESCRIPTION

Diagnosis of T-cell lymphoma and a subset of B-cell lymphoma

STAIN NAME

CD44

ANTIBODY

DF1485

DESCRIPTION

Transitional carcinoma-in-situ vs. non-neoplatic changes in the urothelium

STAIN NAME

CD45 (LCA)

ANTIBODY

2B11+PD7/26

DESCRIPTION

Labels all hematopoietic cells

STAIN NAME

CD5

ANTIBODY

SP19

DESCRIPTION

Useful in the identification of B-cells, MCL, HCL, CLL/SLL, T-cells, thymic carcinomas

STAIN NAME

CD56

ANTIBODY

123C3

DESCRIPTION

Neuroedrocrine marker, NK cells

STAIN NAME

CD68

ANTIBODY

KP1

DESCRIPTION

Labels macrophages myeloid precursors, preipheral blood granulocytes

STAIN NAME

CD7

ANTIBODY

Clone: CBC.37

DESCRIPTION

Lables immature and mature T-lymphocytes and T-cell Leukemia

STAIN NAME

CD79a

ANTIBODY

Pan B-cell JBC1171

DESCRIPTION

Acute leukemias, B-cell lymphomas, and in some myelomas

STAIN NAME

CD99

ANTIBODY

12E71

DESCRIPTION

Expressed by Ewing’s sarcoma cells and lymphoblastic leukemia/lymphoma

STAIN NAME

CDX2

ANTIBODY

DAK-CDX2

DESCRIPTION

Expressed in primary and metastatic colorectal and gastric carcinomas

STAIN NAME

CEA

ANTIBODY

Carcinoembyronic Antigen

DESCRIPTION

Useful in identifying the origin of various metastatic adenocarcinomas

STAIN NAME

Chromogranin A

ANTIBODY

Chromogranin A (polyclonal)

DESCRIPTION

Useful in identification of neuroendocrine tumors

STAIN NAME

CK19

ANTIBODY

RCK 108

DESCRIPTION

Useful in the distinction of liver metastasis from hepatocellular carcinomas

STAIN NAME

CK20

ANTIBODY

Ks20.8

DESCRIPTION

Found in colon, ovarian, stomach, bile, pancreas and Merkel Cells

STAIN NAME

CK5/6

ANTIBODY

D5 / 16B4

DESCRIPTION

Labels mesotheliomas, transitional and squamous cell carcinomas

STAIN NAME

CK7

ANTIBODY

OV-TL 12/30

DESCRIPTION

Identify positive lung and breast and negative colon and prostate cells

STAIN NAME

CK903

ANTIBODY

34bE12

DESCRIPTION

Can be used for the identification of basal cell layer in prostate tissue

STAIN NAME

CMV

ANTIBODY

DDG9 + CCH2

DESCRIPTION

Useful in identification of CMV infection

STAIN NAME

Collagen IV

ANTIBODY

CIV 22

DESCRIPTION

Useful in detecting the loss of parts of basement membrane in carcinomas

STAIN NAME

D2-40

ANTIBODY

D2-40

DESCRIPTION

Lymphatic invasion of primary tumors; seminomas and mesotheliomas

STAIN NAME

Desmin

ANTIBODY

D33

DESCRIPTION

Reacts with leiomyosarcomas and cells such as rhabdomyosarcomas

STAIN NAME

Dog-1

ANTIBODY

DOG1.1

DESCRIPTION

Used as a very sensitive and specific marker for GIST

STAIN NAME

EBER-ISH

ANTIBODY

ISH

DESCRIPTION

Used in the detection of the Epstein Barr Virus (EBV) RNA

STAIN NAME

EBV

ANTIBODY

CS.1-4

DESCRIPTION

Used in the detection of the Epstein Barr Virus (EBV)-positive lymphoblastoid cell lines and
EBV infected B-cell immunoblasts in infectious mononucleosis

STAIN NAME

E-cadherin

ANTIBODY

NCH-38

DESCRIPTION

Useful in the differentiation of ductal and lobular carcinomas of the breast

STAIN NAME

EMA

ANTIBODY

E29

DESCRIPTION

Stains normal and neoplastic cells from various carcinomas

STAIN NAME

ER

ANTIBODY

EP1

DESCRIPTION

Predicts response of breast cancer to anti-hormonal therapy, such as tamoxifen

STAIN NAME

ERG

ANTIBODY

EP111

DESCRIPTION

Used to identify prostate carcinoma; also as an endothelial cell marker

STAIN NAME

Factor VIII (vWF:Ag)

ANTIBODY

polyclonal anti-VWF

DESCRIPTION

Diagnosis of vascular neoplasms

STAIN NAME

Factor XIIIa

ANTIBODY

E980.1

DESCRIPTION

Differentiate between dermatofibroma and dermatofibrosarcoma

STAIN NAME

GATA3

ANTIBODY

GATA3

DESCRIPTION

Used in the IHC workup panel for unknown primary carcinomas, when carcinomas of the breast or urinary bladder are a possibility

STAIN NAME

GCDFP-15

ANTIBODY

Gross Cystic Disease Fluid Protein

DESCRIPTION

Breast carinoma, salivary duct carcinoma and apocrine epithelia

STAIN NAME

GFAP

ANTIBODY

polyclonal

DESCRIPTION

Differentiate the primary gliomas from metastatic lesions in the brain

STAIN NAME

Glypican-3

ANTIBODY

Glypican-3

DESCRIPTION

Differentiate hepatocellular carcinomas from normal liver tissue and benign hepatic lesion

STAIN NAME

HBME-1

ANTIBODY

(clone HBME-1)

DESCRIPTION

Reacts with mesothelial cells, mesotheliomas and some (20-30%) carcinomas

STAIN NAME

h-Caldesmon

ANTIBODY

h-CD

DESCRIPTION

Helps identify smooth muscle tumors

STAIN NAME

HCG(chorionic gonadotropin)

ANTIBODY

Polyclonal

DESCRIPTION

Identification of gestational trophoblastic tumors derived from the placenta

STAIN NAME

Helicobacter pylori

ANTIBODY

B0471

DESCRIPTION

Reacts with H. pylori on the surface of epithelial cells of stomach biopsies

STAIN NAME

HEP-PAR1 (Hepatocyte)

ANTIBODY

OCH1E5

DESCRIPTION

Differentiate hepatocellular carinomas from adenocarinomas

STAIN NAME

HER2 DISH

ANTIBODY

DNA Probe

DESCRIPTION

HER2 protien over-expression and aids in assessment of patients being considered for Herceptin treatment

STAIN NAME

HER2 IHC

ANTIBODY

Herceptest

DESCRIPTION

HER2 protien over-expression, patients may benefit from trastuzumab (Herceptin) therapy

STAIN NAME

Hgb A

ANTIBODY

Polyclonal

DESCRIPTION

Useful in the detection of red blood cell precursors

STAIN NAME

HHV-8

ANTIBODY

13B10

DESCRIPTION

Identification of the latent nuclear protein of the human herpes virus 8 in Kaposi’s Sarcoma,
multicentric Castleman’s disease, and primary effusion lymphoma

STAIN NAME

HMB 45

ANTIBODY

HMB45

DESCRIPTION

Expressed on melanomas and tumors of melanocytic differentiation

STAIN NAME

HSV1

ANTIBODY

Polyclonal

DESCRIPTION

Detection of HSV 1 in human cellular material

STAIN NAME

HSV2

ANTIBODY

Polyclonal

DESCRIPTION

Detection of HSV 2 in human cellular material

STAIN NAME

Inhibin

ANTIBODY

R1

DESCRIPTION

Differentiation between adrenocortical tumors and renal cell carcinoma

STAIN NAME

Kappa- ISH

ANTIBODY

DNA Probe

DESCRIPTION

Reacts with immunoglobulin Kappa-light chain mRNA

STAIN NAME

Kappa Light chain

ANTIBODY

Polyclonal

DESCRIPTION

Reacts with immunoglobulin Kappa-light chain

STAIN NAME

Kappa/Lambda Double stain

ANTIBODY

KDB-1 + N/A

DESCRIPTION

Differentiation between Kappa and Lambda by IHC

STAIN NAME

Kappa/Lambda Double stain – ISH

ANTIBODY

DNA Probe

DESCRIPTION

Differentiation between Kappa and Lambda by mRNA.

STAIN NAME

Ki67

ANTIBODY

MIB-1

DESCRIPTION

Labels proliferating cells in late G1-, S-, M-, and G2 phases of the cell cycle

STAIN NAME

Lambda Light chain

ANTIBODY

Polyclonal

DESCRIPTION

Reacts with immunoglobulin Lambda-light chain

STAIN NAME

Lambda- ISH

ANTIBODY

DNA Probe

DESCRIPTION

Reacts with immunoglobulin Lambda-light chain mRNA

STAIN NAME

Lysozyme (Muramidase)

ANTIBODY

Polyclonal

DESCRIPTION

Helps to identify myeloid cells, monocytes, histiocytes, and poorly differentiated leukemic
monoblasts. Lysozyme is also expressed in myeloproliferative disorders.

STAIN NAME

Mammaglobin

ANTIBODY

304-1A5

DESCRIPTION

Useful in the identification of breast carcinoma

STAIN NAME

Melan A

ANTIBODY

A103

DESCRIPTION

Melanomas, adrenocortical carincomas and sex cord tumors of the gonads

STAIN NAME

Microinvasion cocktail (CK5/6, p63, CK8/18)

ANTIBODY

CK 5/6 & p63 with CK8/18

DESCRIPTION

Distinguishing DCIS from microinvasive breast carcinoma

STAIN NAME

MITF

ANTIBODY

MITF

DESCRIPTION

Aids in the classification of melanoma

STAIN NAME

MMR IHC Panel for MSI (MLH1, MSH2, MSH6, PMS2)

ANTIBODY

ES05,F811,EP49, EP51

DESCRIPTION

Absence correlates with a mismatch repair gene defect in the respective gene

STAIN NAME

MOC31

ANTIBODY

MOC 31

DESCRIPTION

Helps to differentiate carcinomas from mesotheliomas

STAIN NAME

MPO

ANTIBODY

Myeloperoxidase

DESCRIPTION

Useful in differentiating between myeloid and lymphoid leukemias

STAIN NAME

MUM 1

ANTIBODY

MUM1p

DESCRIPTION

Associated with poor prognosis of patients with diffuse large B-cell Lymphoma

STAIN NAME

Myo D1

ANTIBODY

(clone: 5.8A)

DESCRIPTION

Stains majority of rhabdomyosarcomas of various histological subtypes

STAIN NAME

Napsin A

ANTIBODY

Polyclonal

DESCRIPTION

Used in the identification of pulmonary adenocarcinomas

STAIN NAME

NSE

ANTIBODY

BBS/NC/VI-H14

DESCRIPTION

Neuroendocrine tumors

STAIN NAME

Oct-4

ANTIBODY

MRQ-10

DESCRIPTION

High sensitivity and specificity in seminoma/dysgerminoma, embryonal carcinoma and a germ
component of gonadoblastoma

STAIN NAME

P16

ANTIBODY

INK4a

DESCRIPTION

Overexpression reported for some cancer entities

STAIN NAME

P40

ANTIBODY

BC28

DESCRIPTION

Used as an ancillary tool for a diagnosis of pulmonary squamous cell carcinoma

STAIN NAME

P53

ANTIBODY

DO-7

DESCRIPTION

Overexpression associated with high proliferative rates

STAIN NAME

P57

ANTIBODY

Kp10

DESCRIPTION

Useful in the identification of complete moles versus partial mole or hydropic abortus

STAIN NAME

P63

ANTIBODY

BC4A4

DESCRIPTION

Marker of myoepithelial and basal cells

STAIN NAME

Parathyroid Hormone

ANTIBODY

MRQ-31

DESCRIPTION

Anti-PTH antibody is useful to distinguish parathyroid hyperplasia/neoplasms from thyroid and metastatic neoplasms

STAIN NAME

PAX5

ANTIBODY

BC/24

DESCRIPTION

Labels normal and neoplastic B-cells

STAIN NAME

PAX8

ANTIBODY

Polyclonal

DESCRIPTION

Identifies clear cell, chromophobe and papillary renal carcinoma, negative in urothelium; stains tumors of Mullerian origin

STAIN NAME

PD-L1 22C3

ANTIBODY

22C3

DESCRIPTION

Used in non-small cell cancer of lung to see if a patient is eligible for Keytruda®

STAIN NAME

PD-L1 28-8

ANTIBODY

28-8

DESCRIPTION

Used in non-squamous, non-small cell cancer of lung to see if a patient is eligible for Opdivo®.

STAIN NAME

Phosphohistone H3 (PHH3)

ANTIBODY

PHH3

DESCRIPTION

PHH3 is a core histone protein, one of the major proteins that reach a maximum for chromatin
condensation during mitosis; it serves as a mitotic marker to separate mitotic figures from
apoptotic bodies and karyorrhectic debris (due to their lack of phosphorylations)

STAIN NAME

PIN4 Triple Stain (CK5/14, p63, P504S)

ANTIBODY

P504S (AMACR) & P63 & HMW CK (XM26 + LL002 + BC4A4 + N/A)

DESCRIPTION

Helps with diagnosing prostatic intraepithelial neoplasia

STAIN NAME

PLAP

ANTIBODY

8A9

DESCRIPTION

Useful in the identification of seminoma and embryonal carcinomas

STAIN NAME

PR

ANTIBODY

PgR 636

DESCRIPTION

Predicts response of breast cancer to anti-hormonal therapy, such as tamoxifen

STAIN NAME

PRAME

ANTIBODY

EPR20330

DESCRIPTION

Preferentially expressed antigen in melanoma. An autosomal cancer-testis antigen (CTA) gene.

STAIN NAME

PSA

ANTIBODY

Polyclonal

DESCRIPTION

Useful in the identification of metastasis or prostatic origin

STAIN NAME

RCC

ANTIBODY

SPM314

DESCRIPTION

Expressed in renal cell carcinomas and normal kidney tissue

STAIN NAME

S100

ANTIBODY

Polyclonal

DESCRIPTION

Schwannomas, ependymomas, astrogliomas, benign/malignant melanomas

STAIN NAME

SMM-HC

ANTIBODY

SMMS-1

DESCRIPTION

Labels smooth muscle and myoepthithelial cells, and sclerosing breast lesions

STAIN NAME

SOX-10

ANTIBODY

BC34

DESCRIPTION

Sensitive marker for neoplasms of neural crest origin (eg Melanoma) and does not label
carcinomas

STAIN NAME

SOX-11

ANTIBODY

MRQ-58

DESCRIPTION

Specific marker for cyclin D1-positive and cyclin D1-negative MCL

STAIN NAME

Synaptophysin

ANTIBODY

DAK-SYNAP

DESCRIPTION

Identification of normal neuroendocrine cells and neuroendocrine neoplasms

STAIN NAME

TdT

ANTIBODY

Polyclonal

DESCRIPTION

Helpful for the diagnosis of acute lymphoblastic lymphoma/leukemias

STAIN NAME

Thrombomodulin

ANTIBODY

1009

DESCRIPTION

Labels most mesotheliomas with a membranous staining pattern

STAIN NAME

Thyroglobulin

ANTIBODY

Polyclonal

DESCRIPTION

Identification of thyroid carcinomas of the papillary and follicular types

STAIN NAME

TTF-1

ANTIBODY

8G7G3/1

DESCRIPTION

Reactive with normal and neoplastic thyroid and lung adenocarcinomas

STAIN NAME

TTF-1/Napsin A (Double stain) lung adenocarcinoma

ANTIBODY

8G7G3/1 + NA

DESCRIPTION

A useful marker for identifying lung adenocarcinoma

STAIN NAME

Vimentin

ANTIBODY

V9

DESCRIPTION

Mesenchymal cells, lymphocytes, sarcomas, melanomas

STAIN NAME

WT1

ANTIBODY

6F-H2

DESCRIPTION

Mesothelioma, ovarian serous tumors, renal cell carcinoma, and Wilm’s tumor